The CFM Technology
The Continuous Flow Microspotter™ (CFM) is a patent-pending technology that uses flow to deposit biomolecules on biosensor surfaces. Unlike other systems which deposit droplets of material en masse onto a surface, the CFM uses flow to cycle molecules back and forth over the surface, yielding optimal binding from crude or dilute solutions. As a result, the CFM enables up to 10,000 fold enhancements in sensitivity and printing at concentrations 1,000 fold more dilute than competing technologies.
Benefits of Printing with Flow
- Print from dilute solutions by concentrating material onto the slide surface
- CFM printing head seals around each spot, eliminating background and cross talk
- Print directly from complex solutions, capturing only the molecule of interest
- Print low abundance secreted proteins or phage display antibodies directly from crude media
- Print DNA, proteins, cells, carbohydrates, lipids, and more
- Each sample is isolated in its own hydrated microenvironment, preventing denaturation
- Higher assay sensitivity
- Improved spot morphology and uniformity
- Deliver multiple solutions across each spot in series